The novel scratch analyzer, SCLABA-REAL, calculates “frame-to-frame difference” that is a mouse’s migration area per frame by capturing animal behavior at the rate of 240 frames per second using an innovative high-speed camera containing an image processing system. The whole system quantifies the number and duration of scratching behavior automatically by time course analysis of the “frame-to-frame difference” and evaluate the degree of itching from many directions.
You can perform prolonged measurements because the stress on mice from the preliminary treatment and environment is excluded. The timer which activates the system automatically enables it to start analysis at night.
Although scratching behavior is a critical item for the drug development, its quantification by visual check has been subjective. However, the SCLABA-REAL provides automatic objective and accurate analysis of scratching behavior.